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It refers to any visible blemish may well occur, on the surface of the stone. The symptoms of scleroderma can vary dramatically, depending on which organs are affected and how severely.
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However previous studies have shown that low-doses of aspirin are cardio protective; however the effect of high-doses is not known. This study showed that these drugs increased heart disease risks even in healthy people. Discontinuation rates were similar for all three drugs, though.
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